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Tier – A Champs (also known as Beyond God Tier Champions)

Utility = Power Control, Purification, Immunity, armor break, etc..

Champions Reason Condition
Ægon Damage
Utility
Duped
High Signatures
Combo-Dependent
Apocalypse Special Damage
Debuffs
Utility
Ramp Up
OR Synergy
Black Cat Utility
Fair Damage
None
Black Widow (CV) Utility
Fair Damage
Debuffs
None
Captain America IW Utility
Damage
Debuffs
Better with Synergy
(Class Based)
High Signatures
Captain Marvel Movie Utility
Damage
Debuffs
None
Corvus Glaive Utility
Damage
Ramp Up
Duped
Cosmic Ghost Rider Utility
Damage
None
Doctor Doom Utility
Damage
None
Domino Utility
Damage
Synergy
(Red Hulk+Masacre)
Ghost Utility
Damage
Synergy
(Wasp)
Guillotine 2099 Utility
Damage
Ramp Up
Human Torch Utility
Damage
Against Energy Attack
Hercules Utility
Damage
Duped
Hyperion Utility
Damage
Duped
Kingpin Utility
Damage
Better High Sigs
and Hood Synergy
Magneto (Red)
Utility
Special Damage
None
Nick Fury Utility
Damage
Duped
Quake Utility Skilled Player
Shang-Chi Utility
Damage
Better Duped
Stryfe Utility
Damage
Ramp Up
Void Utility
Damage
Debuffs
Duped
Better High Signatures

Let’s have a look at other tiers champions

Tier – B Champions (also known as Solid God Tier Champions)

Angela Utility
Damage
High Signatures
Abomination
(Immortal)

Damage
Utility
Duped
Archangel Nero/Poison
Ability Accuracy
High Signatures
Blade Bleed Damage
Ability Accuracy
Regeneration
Better with
GR and Stark
Synergy
Captain Britain Special Damage
Utility
Defensive Ability Accuracy
None
Colossus Damage
Utility
None
Crossbones Damage
Ability Accuracy
Utility
High Signatures
Better with Synergy
Cull Obsidian Damage High Signatures
Falcon
Damage
Utility
High Signatures
Guardian Special Damage
Utility
High Signatures
Havok Special Damage
Utility
None
Hit Monkey Damage
Utility
None
Howard the Duck
Damage
Utility
None
Hulkbuster Damage
Ability Accuracy
Utility
Better High Sigs
Hulk (Immortal) Damage
Utility
Good Skill
Suicide
Jabari Panther Damage
Utility
None
Kitty Pryde Utility
Damage
Dupe
Longshot Special Damage
Utility
None
Medusa Damage
Utility
Duped
Mister Negative Damage
Utility
Need Good Skill
Misty Knight Damage
Utility
Better Duped
Mole-Man Damage
Utility
None
Namor Damage
Utility
200 Signatures
Omega Red
Damage
Utility
High Signatures
Suicide
Against Non-Robotic
Omega Sentinel Damage
Utility
Better Duped
Peni Parker Damage
Utility
None
Professor X
Utility
Special Damage
Duped
Rintrah Utility
Special Damage
Better High Sigs
Sabretooth Damage  Ramp Up
Sasquatch Synergy
Scarlet Witch Damage
Utility
High Signatures
Scorpian Damage
Utility
None
Sentinel Damage
Utility
None
She-Hulk Damage
Utility
Needs Duped For-
Some Utility
Sorcerer Supreme Ability Accuracy
Utility
Needs Duped For-
Ability Accuracy
Spider-Ham Damage
Utility
None
Spider-Man (Stark) Damage
Utility
Better Duped
Spider-Man (Stealth) Damage
Utility
Better High Sigs
Spider-Man (Miles Morales)
Damage
Utility
Better Duped
Sunspot Damage
Utility
None
Symbiote Supreme Damage
Utility
None
Thing Damage
Utility
High Signatures
Tigra Damage
Utility
High Signatures
Skilled Player
Valkyrie Damage
Utility
High sigs needed
to unlock utility
Venom the Duck Damage
Utility
Ramp Up
Warlock L2 Damage
Utility
Better Duped
Wolverine (Weapon X) Damage
Utility
Better Duped

Tier – C Champions (also known as God Tier Champions)

Champions Reason Condition
Anti-Venom Damage
Utility
Better High Sigs
Black Panther (Classic) Damage
Utility
High Signatures
Black Widow (DO) Damage
Utility
None
Bishop
Damage
Utility
Better with Storm &
Cyclops Synergy
Cable Damage
Utility
Apocalypse Synergy
Captain America (Sam Wilson) Utility
Ability Accuracy
For Good Damage:
CapIW Synergy
High Signature
Diablo
Damage
Utility
Better Duped
Doctor Voodoo
Poison Damage
Ability Accuracy
Utility
High Signatures
Dragon Man Utility
Damage
None
Elsa Bloodstone Utility
Damage
Better High Sigs
Emma Frost Utility
Damage
None
Gamora
Utility
Damage
None
Gorr Utility
Damage
High Sigs
Gwenpool Utility Duped
Hela Damage Odin Synergy
Hulkling Utility
Damage
Better duped
Ikaris Utility
Damage
None
Iron Man Infinity War (IMIW)
Utility
Damage
High Signatures
Killmonger Damage
Utility
High Signatures
Knull Damage
Utility
Better High Sigs
Magik Utility Better Max Sigs
Mojo
Utility
Damage
High Signatures
Nimrod Utility
Damage
Better Duped
Red Hulk
Utility
Damage
None
Sauron Utility
Damage
Better Duped
Sersi Utility
Damage
Better Duped
Silver Surfer Utility
Damage
High Signatures
Spider-Man (2099)
Utility
Damage
None
Star-Lord
Damage High Signatures
Storm (Pyramid X) Special Damage
Utility
None
The Hood One-Off Damage
Utility
None
Toad Damage
Utility
Duped
Ultron (Prime)
Damage
Utility
Better Duped
Venom Damage
Utility
None
Vision (Aarkus)
Damage
Utility
None
Venompool Damage Better Duped
Wiccan Damage
Utility
Need Good Skill
Wolverine Damage
Utility
Suicide
Wong Utility None

Champions That Changes its tier with Apocalypse Synergy (Only when used as Horseman)

Champions Changed Tier
Archangel Tier A
Gambit Tier B
Havok Tier A
Professor X Tier A
Storm Tier B
Sunspot Tier A
Storm (Pyramid X) Tier A
Wolverine Tier B

Tier – D Champions (also known as High Demi-God Tier Champions)

* – Champions with * sign is available as 4-star only, and you can max them out.
D – Must be Duped.
S – Required More Signature.
T – Requires Synergy Team.

Abomination ( T )
(Red Guardian)
Civil Warrior  Carnage
Deadpool (X Forcer) Daredevil (H.K.) Darkhawk ( )
Doctor Octopus Gambit Ghost Rider
Guillotine Hawkeye ( D ) Hulk Ragnarok (Gulk)
Iceman Invisible Woman Jubilee
Karnak Kraven ( D ) King Groot ( D )
Luke Cage ( D ) Masacre Magneto (White)
Mephisto Mister Fantastic ( T )
(F4 Team)
Morningstar ( )
Mysterio Nebula Night Thrasher ( )
Old-Man Logan Proxima Midnight ( ) Punisher 2099
Red Guardian ( ) Rogue Ronin
Sasquatch Silver Centurion Scarlet Witch (New)
Spider Gwen Squirrel girl Terrax ( )
The overseer Thor (Jane Foster) Thor Ragnarok )
Vision OG ( ) Vulture Wasp
War Machine Winter Soldier ( T )
(Killmonger)
 Wolverine ( )
Wolverine -X23     

Tier – E Champions (also known as Low Demi-God Tier Champions)

Annihilus America Chavez Black Widow ( )
Black Bolt ( ) Dormammu
Ebony Maw Joe Fixit Kang ( T )
(Apocalypse)
Man-Thing Nova ( ) Odin ( )
Phoenix Psylocke Purgatory
Storm ( ) Taskmaster ( ) Thor ( )
Thor Ragnarok ( ) Vision  AOU (  ) Yellowjacket ( )
Yondu    

Tier – F Champions (also known as Good Tier OR Useful Tier Champions)

Air Walker Captain Marvel ( ) Daredevil OG ( )
Deadpool Drax Electro ( )
Electra Goldpool
Heimdall Hulk ( )
Kamala Khan ( )     Korg
Loki Mangog MODOK
Ms. Marvel ( ) Nightcrawler Mister Sinister ( )
Mordo Platinumpool Psycho-Man
Red Goblin Red Skull Rocket Raccoon
Ronan ( ) Sentry Super-Skrull
Spider-Man (Symbiote) The Champion Ultron OG
Unst. Colossus ( )    

Tier – G Champions (also known as Fair Tier or Occasionally Useful Tier Champions)

Agent Venom Ant-Man ( ) Beast ( )
Black Panther (CW) Captain America (WWII) Captain America
Cyclops (both)
Dr. Strange ( ) Green Goblin
Iron Fist ( )
Punisher Rhino Spider-Man OG
Thanos    

Tier – H Champions (also knows as Worst Tier or Meme Tier Champions)

Groot Iron-Man Iron Patriot
Juggernaut Moon Knight Superior Iron-Man
     

Note to Readers:
Please note that we have now created the list based on our own research and it has nothing to do with the list created by Seatin Man of Legends guy.